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KMID : 0370219640080010001
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Yakhak Hoeji
1964 Volume.8 No. 1 p.1 ~ p.5
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Metabolic fate of chloramphenicol-ester
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한병훈/Han BH
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Abstract
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Present experiment in vivo shows that some conversions of active groups in chloramphenicol residue of ester, that is hydrolytic cleavage of dichloracetamide and glucuronide formation, seem to take place prior to hydrolysis. This result suggest that the enzymatic hydrolysis rate in vitro, is not available as an index for the evaluation of the chloramphenicol ester potency.
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